Notchsignaling相关论文
Retinal damage in the adult zebrafish induces Müller glia reprogramming to produce neuronal progenitor cells that proli......
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The Impaired Intestinal Mucosal Immunity of IUGR Neonatal Piglets Is Probably Regulated by microRNAs
Intrauterine growth restriction (IUGR) impairs neonatal immunity.However, the inner mechanisms of this impairment are un......
Osteosarcoma(OS)is the most common primary malignancy of bone and is usually associated with poor prognosis due to its h......
Notch signaling induced Endothelial mesenchymal transition contribute to unilateral ureteral obstruc
Renal fibrosis is the final outcome of all progressive kinds of chronic kidney disease.The aim to explore the mechanism ......
Notch signaling modulates proliferative vitreoretinopathy via regulating retinal pigment epithelial-
Purpose To observe tbe involvement of Notch signaling in the epithelial-mesenchymtal transition(EMT)of retinal pigment e......
Inhibition of Notch signaling leads to increased intracellular ROS by upregulating Nox4 expression i
The essential roles of Notch pathway in angiogenesis have been reported for years.However, how Notch pathway plays its r......
Down-regulation of Notch-1 by γ-secretase inhibitor suppress the proliferation and migration of pros
Notch-1 signaling is crucial for stem cell maintenance and in a variety of tissues.Previous research has demonstrated th......
RBP-Jk involved in neointema formation in Chronic Kidney Disease-Induced AVF Failure through regulat
The most favored vascular access for hemodialysis of patients with chronic kidney disease(CKD) is an arteriovenous fistu......
The coumarin osthole stimulates adult neural stem cells, promotes neurogenesis in hippocampus of the
It is believed that neuronal death caused by abnormal deposition of amyloid-beta (Aβ) peptide is the major cause for th......
Notch-RBP-J signaling is required by bone marrow stromal cells for the treatment of acute graft vers
Recent evidence has shown that bone marrow stromal cells (BMSCs) may exhibit immuno-suppression activities through solub......
Different roles of Notch signaling in the development of dorsal root ganglion and trigeminal ganglio
Somatosensory ganglia including dorsal root ganglion (DRG) and trigeminal ganglion (TG) are derived from a common pool o......
Function of Nerfin-1 in preventing medulla neurons dedifferentiation requires its inhibition of Notc
Drosophila larval central nervous system comprises the central brain,ventral nerve cord and optic lobe.In all these regi......
Notch signaling modulates proliferative vitreoretinopathy via regulating retinal pigment epithelial-
Purpose To observe the involvement of Notch signaling in the epithelial-mesenchymal transition(EMT)of retinal pigment ep......
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Angiogenesis plays a pivotal role in the formation and homeostasis of blood vessels during embryonic and postnatal d......
The delicate balance between self-renewal and differentiation needs to be exquisitely regulated to maintain tissue h......
Notch signaling modulates the metabolic reprogramming to regulate MDSCs development and suppress tum
Tumor-associated macrophages(TAMs)and Myeloid derived suppressor cells(MDSCs)contribute greatly to hallmarks of canc......
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Resident macrophages contribute to the hepatocellular carcinoma(HCC) development more than bone marr
In recent years,the origin of macrophages in normal organs and tissues has attracted increasingly more attention.Bes......
Disruption of Notch signaling aggravates irradiation-induced bone marrow injury, which is ameliorate
Physical and chemical causes-induced bone marrow (BM) damage often leads to lethality due to neutropenia, thrombocyt......
Arl4aa is required for initiation of definitive hematopoiesis by maintaining Golgi complex integrity
ADP-ribosylation Factor Like 4aa(arl4aa)is a member of ADP ribosylation factor(ARF)family,a group of GTPases control......
Notch signaling is one of the most important pathways mediating cell determination and differentiation.In this study, th......
Notch信号通路是人体重要信号通路,其信号分子在机体内的各个器官中均有表达,其作用涉及细胞周期调节、细胞增殖及凋亡.皮肤作为人......
Notch信号是一进化上保守的细胞间信号转导通路,调控细胞的增生、分化组织构型等过程,在发育期间对细胞的生死起决定性作用.最近的......
Notch 信号通路参与机体多种细胞的凋亡调控，有证据表明在牙齿发育、牙齿损伤与修复、以及口腔肿瘤中均有 Notch 信号参与并可能与......
目的 揭示穴贴对幼鼠早期急性牙髓的保护作用,为中医穴贴干预乳牙保健奠定实验基础.方法 选取48只1月龄幼鼠,雌雄各半,将幼鼠随机......
目的 探讨Notch受体阻断剂MW167对胶质瘤细胞系U87增殖及凋亡的影响.方法 采用四甲基偶氮唑蓝(MTT)法检测MW167对体外培养的胶质瘤......
